Precision Surface Microtopography Regulates Cell Fate via Changes to Actomyosin Contractility and Nuclear Architecture
نویسندگان
چکیده
منابع مشابه
Actomyosin contractility rotates the cell nucleus
The cell nucleus functions amidst active cytoskeletal filaments, but its response to their contractile stresses is largely unexplored. We study the dynamics of the nuclei of single fibroblasts, with cell migration suppressed by plating onto micro-fabricated patterns. We find the nucleus undergoes noisy but coherent rotational motion. We account for this observation through a hydrodynamic approa...
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ژورنال
عنوان ژورنال: Advanced Science
سال: 2021
ISSN: 2198-3844,2198-3844
DOI: 10.1002/advs.202003186